Writer-director Nicole Holofcener's bittersweet tale examines the evolving lives of four female friends living in Los Angeles: married and financially secure Jane (Frances McDormand), Franny (Joan Cusack) and Christine (Catherine Keener), and their single friend Olivia (Jennifer Aniston). As the friends move from one group event to the next, married life starts showing cracks for Jane, Franny and Christine, while Olivia struggles to find herself.