Utilizing state-of-the art forensic technology, Gil Grissom (William Petersen), Catherine Willows (Marg Helgenberger) and fellow detectives with the Las Vegas Police Department's Crime Scene Investigations bureau skillfully solve Sin City's most baffling murder cases. In each episode of this crime drama, CSI squad members contribute their expertise while meticulously analyzing hair, fibers, blood splatter, audio-visuals and other materials.